Thursday, November 22, 2012

pertussis disease

Pertussis is Bordetella pertussis bacteria highly contagious respiratory disease.

It has long been more than 50 years, put the incidence of pertussis in the countries 90% reduction in more than one (1) was observed.

What began as a disease of young children, the disease can be hard at any age. Particularly in children under 6 months old, a dramatic and fatal.


Pathogen Bordetella pertussis cough for pertussis (BP), it is difficult to cultivate, and the growth of gram-negative bacilli, which must be protected.

Bordetella pertussis, a strong affinity to the mucous membranes of the respiratory tract of humans. Pathogenic for humans. Bordetella pertussis toxin produced such a variety of biologically active antigens. Whooping cough is a disease that is largely due to the toxin. Bacteria adhered to the ciliated epithelium of the respiratory tract, respiratory paralyzes cilia and produce toxins that cause inflammation.

After an incubation period of 7-10 days, sensitive (unprotected) begins with flu-like symptoms. These symptoms are typical cases, seizures after a period of deep breathing in a condition characterized by episodes of coughing. The disease is usually diagnosed at this stage. Episodes of coughing, cyanosis and apnea patients can be seen. Coughing, vomiting and fatigue that often follows.

In most cases, the patients are normal between coughing fits.

On average, 15 times in a 24-hour bouts of coughing often occurs at night. The active phase is increased first 2 weeks, 2-3 weeks, and then a plateau is reduced (2.3, 4).

Protect young people, adults and partially by the vaccine less severe forms of the disease, but these people are. On sensitive subjects, mostly children (3b)

Children, especially younger children are very complex forms of the disease. The most common complication and the leading cause of death, secondary bacterial lung disease. Neurological complications such as seizures and encephalopathy are common for infants (3).

90% of the data on deaths from pertussis Lair? Li found that children under 6 months old (3).

Other, more serious complications, acute otitis media, refuses to eat and dehydration occurs. The cough may also occur due to mechanical complications (pneumothorax, epistaxis, hernia, etc.). (3D).

For symptomatic treatment of whooping cough.

Antibiotics are given to reduce the pollution and destruction of microorganisms for the relief (3e).