Thursday, July 14, 2011

Smallpox

Smallpox is a contagious disease to humans, caused by a minor of the two variants of the virus, variola major and variola. The disease is also supported by the Latin names Variola Virus or belief, which is a derivation of Latin VARIUS, which means "spotted" or varus, meaning "pimple" is known. The term "smallpox" was first introduced in Europe in the 15th century used to distinguish from smallpox "great pox" (syphilis).
Smallpox localizes in small blood vessels in the skin, mouth and throat. In the skin, it results in a characteristic maculopapular rash, and then raised fluid-filled blisters. V. major produces more serious disease and mortality by 30-35%. V. minor causes a mild form of disease (also known as white pox, cottonpox, white pox, whitepox known and Cuban itch) which kills about 1% of their victims. Long-term complications of infection include characteristic scars V. major, usually on the face, occurring in 65-85% of survivors. Blindness from corneal ulceration and scarring, and limb deformities due to arthritis and osteomyelitis are less common complications seen in about 2-5% of cases.
Smallpox is believed to have emerged in human populations about 10,000 BC. Early evidence of smallpox is likely to pustules on the mummified body of Pharaoh Ramesses V of Egypt. Illness killed nearly 400 000 Europeans each year during the last years of the 18th century (including five monarchs), and was responsible for one third of all those infected, 20-60% and 80% of HIV-infected children have died from the disease blindness. Of. Smallpox was responsible, an estimated 300-500 deaths in the 20th Century. Only in 1967, according to the World Health Organization (WHO) reported that 15 million people contracted HIV, and that two million people have been killed this year.
After immunization campaigns in the 19th and 20th centuries, the WHO smallpox eradication in 1979 is certified. Smallpox was eradicated one of the two infectious diseases, rinderpest and other, which was declared eradicated in 2011.