Acute illness causes liver inflammation, vomiting, jaundice and, rarely, death. Chronic hepatitis B may eventually lead to cirrhosis and liver cancer fatal disease with very poor response to current chemotherapy. Infection can be prevented by vaccination.
Hepatitis B virus is a hepadnavirus with a HEPA-hepatotrophic and DNA, because this virus DNA and has a circular genome is partially double-stranded DNA. Virus RNA intermediate by reverse transcription to repeat, and in this respect they are similar to retroviruses. Although replication in the liver, the virus spreads into the blood, where virus-specific proteins and their corresponding antibodies are detected in infected people. Blood tests for these proteins and antibodies, which are used to diagnose infection.